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KMID : 0387419930040010099
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Korean Society of Oriental Neuropsychiatry
1993 Volume.4 No. 1 p.99 ~ p.119
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A study of the comparative effect of Kuibitang , Kamiondarmtang , and Kuibiondarmtang on serum levels in rats under the immobilization stress
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Abstract
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In order to compare and examine the effect the effect of Kuibitang, Kamiondarmtang and Kuibiondarmtang against stress, I induced immobilization stress by binding rats for 200mins under a little anesthetized with ether. I classified as normal group, control group which administrated 0.9% NaCl solution, sample A group which administrated Kuibitang, sample B group which administrated Kamiondarmtang and sample C group which administrated Kuibiondarmtang. I got some conclusions by measuring amounts of norepinephrine, epinephrine, triiodothyronine(T) and thyroxine(T) in 1, 3 and 5 days, respectively.
1. Norepinephrine showed high meaningful decrease after 1. 3 and 5 days in sample A group. It showed little decrease in sample B group. It showed a little meaningful decrease after 1 day and high meaningful decrease after 3 and 5 days in samlpe C group.
2. Epinephrine showed high meaningful decrease after 3 and 5 days in sample A group. It showed little decrease in sample B group. It showed a little meaningful decrease after 3 days and high meaningful decrese after 5 days in sample C group.
3. Triiodothyronine(T) inclined to approach normal value in sample A, B, C group in comparision wit control group but didn´t have high meaning.
4. Thyroxine(T) inclined to approach normal va1ue in sample A, B, C group in comparrision with contrl group but didn´t have high meaning.
As I consider the effect of experiments, I think that Kuibitang and Kuibiondarmtang have some effects against stress and it is right to apply to the treatment of stress.
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KEYWORD
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